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Macrophages are white blood cells within tissues, produced by the differentiation of monocytes.
Monocytes and macrophages are phagocytes, acting in general immunity. They also trigger specific defense mechanisms (adaptive immunity) of vertebrates.
Their role is to phagocytose (engulf and then digest) cellular debris and pathogens either as stationary or as mobile cells. They also stimulate lymphocytes and other immune cells to respond to the pathogen, view more...